SciELO - Scientific Electronic Library Online

vol.62Intellectual skills needed for the effective learning and application of chemical knowledgeSynthesis and cytotoxicity screening of some novel benzofuranoyl-pyrazole derivatives against liver and cervix carcinoma cell lines índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados



Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Em processo de indexaçãoSimilares em Google


South African Journal of Chemistry

versão On-line ISSN 1996-840X
versão impressa ISSN 0379-4350


NAIDU, K. Reddimohan et al. A facile catalyst-free Pudovik reaction for the synthesis of α-amino phosphonates. S.Afr.j.chem. (Online) [online]. 2009, vol.62, pp.185-188. ISSN 1996-840X.

Some imines were synthesized by the reaction of 5-amino 1-naphthol with substituted aromatic aldehydes in ethanol under reflux conditions. Dialkyl phosphites underwent addition with aromatic imines to give novel α-amino phosphonates. All the title compounds were characterized by elemental analysis, IR, 1H, 13C, 31P NMR and mass spectral data. All the newly-synthesized compounds (4a-j) exhibited moderate antibacterial and antifungal activity.

Palavras-chave : 5-Amino-1-naphthol; imines; dialkyl phosphite; α-amino phosphonates; antimicrobial activity.

        · texto em Inglês     · Inglês ( pdf )


Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons