Resumen

BUX, Tasneem et al. An uncommon variant of Alzheimer's disease: Posterior cortical atrophy. S. Afr. j. psyc. [online]. 2025, vol.31, n.1, pp.1-4. ISSN 2078-6786.  https://doi.org/10.4102/sajpsychiatry.v31i0.2420.

INTRODUCTION: This case report highlights one of the less common variants of major neurocognitive disorder because of Alzheimer's disease, posterior cortical atrophy. There is a paucity of data about this condition in sub-Saharan Africa PATIENT PRESENTATION: A 54-year-old female presented to the geriatric clinic following a 2-year history of poor memory and inability to fulfil her work obligations. The most prominent symptom was visual disturbance, with a normal ophthalmic examination MANAGEMENT AND OUTCOME: Workup done to reveal reversible causes of dementia did not yield any positive results. After a full history, physical and cognitive examination and radiological investigations, a diagnosis of posterior cortical atrophy variant of major neurocognitive disorder because of Alzheimer's disease as the most likely aetiology was established CONCLUSION: Posterior cortical atrophy is a rare variant of Alzheimer's disease, and no case reports from South Africa are available in the literature CONTRIBUTION: This case reminds us that unusual presentations of cognitive impairment require a broad differential diagnosis

Palabras clave : posterior cortical atrophy; Alzheimer's dementia; visuospatial apraxia; neurodegeneration; atypical Alzheimer's.

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