Resumo

RICHARDS, L; ISMAIL, F  e  OMAR, S V. Missed rifampicin and isoniazid resistance by commercial molecular assays. SAMJ, S. Afr. med. j. [online]. 2024, vol.114, n.7, pp.14-16. ISSN 2078-5135.  https://doi.org/10.7196/SAMJ.2024.v114i7.1779.

Drug-resistant tuberculosis (TB) has poor outcomes unless resistance is detected early, ideally by commercially available molecular tests. We present a case of occult multidrug-resistant TB where both rifampicin and isoniazid resistance were missed by molecular testing and were only identified by phenotypic testing.

Palavras-chave : Tuberculosis; drug resistance; diagnosis; mutations; molecular markers; challenges.

        · texto em Inglês     · Inglês ( pdf )