Abstract

SONDERUP, M W; MUDINI, W  and  SPEARMAN, C W N. Ivermectin drug-induced liver injury. SAMJ, S. Afr. med. j. [online]. 2023, vol.113, n.6, pp.1203-1204. ISSN 2078-5135.  https://doi.org/10.7196/SAMJ.2023.v113i6.624.

Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID-19 prevention. Liver histology demonstrated a pattern of injury that was both portal and lobular, with a bile ductulitis with marked cholestasis. She was managed with low-dose corticosteroids, later tapered, and withdrawn. She remains well a year after presenting.

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