Abstract

VAN WYK, HJ  and  MUNZHELELE, TI. An evaluation of White Cell count, C-Reactive protein and Procalcitonin as diagnostic and prognostic biomarkers during the management of maxillofacial infections. S. Afr. dent. j. [online]. 2025, vol.80, n.7, pp.363-366. ISSN 0375-1562.  https://doi.org/10.17159/sadj.v80i07.23726.

INTRODUCTION: Odontogenic infections (Oi) and to a lesser extent nonodontogenic infections, constitute a substantial proportion of a maxillofacial and oral surgeon's work. These infections may be life threatening if not treated adequately. Aims and objectives: The purpose of this current study was to evaluate the diagnostic and prognostic value of White Cell count (WCC), C-Reactive Protein (CRP) and Procalcitonin (PCT), in the management of maxillofacial infections DESIGN AND METHODS: Quantitative, descriptive research was conducted to determine whether blood levels of the mentioned parameters, on day one and day three respectively, had any indication of patient's response to treatment received for the presenting infection. Serial blood samples were taken on day 1 and day 3 respectively and values were recorded in a data collection sheet and evaluated using Chi-squared tables with STATA-17 analysis. The results showed that there was a statistically significant reduction in WCC and CRP levels following treatment, however, PCT levels did not change significantly. In conclusion, this current study confirmed that specific blood test parameters, such as WCC and CRP, could be useful in evaluating patient's response to treatment of maxillofacial infections.

Keywords : White Cell Count; C-Reactive Protein; Procalcitonin; Maxillofacial infections.

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