<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0256-9574</journal-id>
<journal-title><![CDATA[SAMJ: South African Medical Journal]]></journal-title>
<abbrev-journal-title><![CDATA[SAMJ, S. Afr. med. j.]]></abbrev-journal-title>
<issn>0256-9574</issn>
<publisher>
<publisher-name><![CDATA[Health and Medical Publishing Group]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0256-95742012000700021</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[The effectiveness of a hospital-based intervention for patients with substance-use problems in the Western Cape]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sorsdahl]]></surname>
<given-names><![CDATA[Katherine]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Stein]]></surname>
<given-names><![CDATA[Dan J]]></given-names>
</name>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Weich]]></surname>
<given-names><![CDATA[Lize]]></given-names>
</name>
<xref ref-type="aff" rid="A04"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fourie]]></surname>
<given-names><![CDATA[David]]></given-names>
</name>
<xref ref-type="aff" rid="A05"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Myers]]></surname>
<given-names><![CDATA[Bronwyn]]></given-names>
</name>
<xref ref-type="aff" rid="A03"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,University of Cape Town Department of Psychiatry and Mental Health ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A02">
<institution><![CDATA[,University of Cape Town Department of Psychiatry and Mental Health ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A03">
<institution><![CDATA[,University of Cape Town Department of Psychiatry and Mental Health ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A04">
<institution><![CDATA[,South African National Council on Alcoholism and Drug Dependence (SANCA)  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="A05">
<institution><![CDATA[,Medical Research Council of South Africa Alcohol and Drug Abuse Research Unit ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>07</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>07</month>
<year>2012</year>
</pub-date>
<volume>102</volume>
<numero>7</numero>
<fpage>634</fpage>
<lpage>635</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.za/scielo.php?script=sci_arttext&amp;pid=S0256-95742012000700021&amp;lng=en&amp;nrm=iso&amp;tlng=en"></self-uri><self-uri xlink:href="http://www.scielo.org.za/scielo.php?script=sci_abstract&amp;pid=S0256-95742012000700021&amp;lng=en&amp;nrm=iso&amp;tlng=en"></self-uri><self-uri xlink:href="http://www.scielo.org.za/scielo.php?script=sci_pdf&amp;pid=S0256-95742012000700021&amp;lng=en&amp;nrm=iso&amp;tlng=en"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[District hospitals regularly experience a high incidence of substance-use disorders, but rarely provide interventions. We describe the effectiveness of an intervention developed and implemented by a Western Cape hospital. Patients with probable substance use were referred to an on-site social worker for an alcohol, smoking and substance involvement screening test (ASSIST), a brief motivational intervention and referral to specialist care. At the 3-month follow-up, the ASSIST was re-administered telephonically. An intervention was received by 127 patients. A significant reduction in substance use was reported in 92 patients who completed a 3-month follow-up evaluation (p<0.001). Of the 60 patients referred to further care, half entered treatment. We conclude that, with minimal resourcing, it is feasible to administer a brief substance-use intervention for patients attending district hospitals.]]></p></abstract>
</article-meta>
</front><body><![CDATA[ <p align="right"><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b>RESEARCH</b></font></p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="4"><b>The effectiveness    of a hospital-based intervention for patients with substance-use problems in    the Western Cape</b></font></p>     <p>&nbsp;</p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b>Katherine Sorsdahl<sup>I</sup>;    Dan J Stein<sup>II</sup>; Lize Weich<sup>IV</sup>; David Fourie<sup>V</sup>;    Bronwyn Myers<sup>III, VI</sup></b></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><sup>I</sup>PhD.    Department of Psychiatry and Mental Health, University of Cape Town    <br>   <sup>II</sup>MD, PhD. Department of Psychiatry and Mental Health, University    of Cape Town    <br>   <sup>III</sup>PhD. Department of Psychiatry and Mental Health, University of    Cape Town    <br>   <sup>IV</sup>FCPsych. Department of Psychiatry, University of Stellenbosch<i>    ]]></body>
<body><![CDATA[<br>   </i> <sup>V</sup>DPhil. South African National Council on Alcoholism and Drug    Dependence (SANCA), Tygerberg    <br>   <sup>VI</sup>PhD. Alcohol and Drug Abuse Research Unit, Medical Research Council    of South Africa </font></p>     <p>&nbsp;</p>     <p>&nbsp;</p> <hr size="1" noshade>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">District hospitals    regularly experience a high incidence of substance-use disorders, but rarely    provide interventions. We describe the effectiveness of an intervention developed    and implemented by a Western Cape hospital. Patients with probable substance    use were referred to an on-site social worker for an alcohol, smoking and substance    involvement screening test (ASSIST), a brief motivational intervention and referral    to specialist care. At the 3-month follow-up, the ASSIST was re-administered    telephonically. An intervention was received by 127 patients. A significant    reduction in substance use was reported in 92 patients who completed a 3-month    follow-up evaluation (p&lt;0.001). Of the 60 patients referred to further care,    half entered treatment. We conclude that, with minimal resourcing, it is feasible    to administer a brief substance-use intervention for patients attending district    hospitals.</font></p> <hr size="1" noshade>     <p>&nbsp;</p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Substance-use disorders    are a major global public health concern. The recent South African stress and    health study (SASH) indicated a high lifetime prevalence (13.3%) and early onset    (21 years) of such disorders,<sup>1</sup> with significantly higher rates in    the Western Cape compared with other provinces. Substance-abuse treatment services    are limited in the Western Cape, where existing services are overwhelmed by    the demand for treatment.<sup>2</sup></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Increasing the    range of treatment services is one way of improving access.<sup>2</sup> The    existing system relies heavily on provision of highthreshold treatment services    by specialist providers; few lowthreshold early-intervention services are available    at a primary healthcare level. This limits access to care as high-threshold    services are costly. More cost-effective lower threshold services are preferable.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Evidence suggests    that screening, brief intervention, and referral to treatment (SBIRT) is effective    for addressing mild to moderate substance-related problems and is feasible to    implement.<sup>3,4</sup> However, there is little evidence for the effectiveness    or feasibility of SBIRT for substance use in South Africa. We describe preliminary    outcomes from a hospital-based SBIRT programme.</font></p>     ]]></body>
<body><![CDATA[<p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="3"><b>Methods</b></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">The SBIRT programme    emerged from the realisation that substance-related psychoses were observed    in more than 80% of the 250 monthly patients seeking psychiatric services in    G F Jooste Hospital (David Fourie, personal communication). A substance-abuse    intervention model was developed by SANCA Western Cape, the Department of</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Social Development,    the Department of Health and Cape Town Drug Counselling Centre. Implementation    of the model saw the initiation of a substance-abuse services centre at the    hospital, staffed by a social worker, an auxiliary social worker and a research    assistant.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Over a 7-month    period, patients referred to the centre were given verbal and written information    about the programme. A modified version of the alcohol, smoking and substance    involvement screening test (ASSIST) was used to screen patients for substance    use.<sup>5</sup> Patients were categorised as low-, moderate- or high-risk depending    on the severity of substance use. Patient sociodemographic information was collected.    Immediately following screening, patients received a brief intervention (based    on motivational interviewing) from the social worker. Motivational interviewing    provides information or advice, motivates a change in substance use and teaches    skills to reduce substance use by behavioural change.<sup>4</sup> High-risk    participants were referred to specialist substance-abuse treatment centres following    intervention, as they were more likely to have substance dependence or related    health conditions.<sup>5</sup></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">An uncontrolled    one-group pre- and post-test outcomes evaluation was performed by an independent    external evaluator. All enrolled participants were evaluated. At the 3-month    follow-up, the ASSIST was re-administered to all patients and a feedback questionnaire    was completed.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b>Outcomes</b></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b>Primary outcome:    substance use</b></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">The ASSIST<sup>5</sup>    - validated in several developing countries - was administered to assess the    extent of problematic substance use. A substance-use involvement score was calculated    for each substance used in the preceding 3 months. In the case of multiple substances,    only the highest score was included in the total score.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b>Secondary outcome:    service satisfaction</b></font></p>     ]]></body>
<body><![CDATA[<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Questions were    developed to assess service satisfaction and investigate potential barriers    to treatment. Reasons for not accessing further treatment were explored in patients    referred elsewhere for further treatment.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Analysis: ÷<sup>2</sup>    statistics and t-tests were used to determine loss to follow-up. Change in substance-use    involvement scores from the pre-to post-test were evaluated using paired-sample    <i>t</i>-tests.</font></p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="3"><b>Results</b></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">A total of 127    substance-use patients received an intervention; 88% were male, 78% were single,    and average age was 30 years. Black African and coloured participants comprised    47% each. The primary substances of abuse were methamphetamine (30%), alcohol    (26%), cannabis (26%), mandrax (9%) and opioids (7%). Multiple substance use    was reported by 44% of participants. Of the 127 patients, 68% received screening,    a brief intervention and referral for specialist treatment for substance abuse;    32% received screening and a brief intervention without referral.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Ninety-two (72%)    participants completed the 3-month follow-up interview. Attrition was not significantly    associated with sociodemographic or substance-related variables. Substance-use    involvement scores decreased significantly following intervention (pre-intervention    mean 37.60&plusmn;8.433, post-intervention mean 17.02&plusmn;17.19, f(72)=10.89,    p&lt;0.001). Reductions were observed in the use of all classes of drugs except    cocaine (p=0.742, <a href="/img/revistas/samj/v102n7/21t01.jpg">Table 1</a>).</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Of the 92 patients    who completed the follow-up, 60 (66%) were referred for further treatment, and    30 (50%) received additional services. Many participants did not provide reasons    for not attending further care. Others reported that they did not require further    treatment or it was a waste of time <i>(n</i>=8), it was too far to travel <i>(n</i>=2),    they had started working <i>(n</i>=2) or they had moved away from the services    (n=1). Of those that attended treatment services, 55% felt that the facility    met their needs, 27% that the facility mostly met their needs, and 18% that    the facility did not meet their needs.</font></p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="3"><b>Discussion</b></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">This evaluation    yielded 3 important outcomes. Firstly, it demonstrated the feasibility and acceptability    of introducing SBIRT for substance use into public hospitals in South Africa,    with minimal requirements for additional resourcing and little burden on health    professionals.</font></p>     ]]></body>
<body><![CDATA[<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Secondly, it provided    preliminary evidence of the effectiveness of SBIRT in reducing illicit drug    use in South Africa. Specifically, the intervention was successful in helping    high-risk users significantly reduce their substance use to moderate levels.    This adds to the limited body of knowledge supporting the effectiveness of SBIRT    for illicit drug use.<sup>3,4</sup></font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Thirdly, the profile    of people using the SBIRT programme differed from those attending specialist    substance-abuse treatment facilities in the province. While there were almost    an equal proportion of black and coloured respondents who received substance-use    services through the programme, black South Africans comprised only 13% of treatment    admissions in specialist substance-abuse facilities in 2010.<sup>6</sup> This    suggests that there are fewer barriers to accessing substance-abuse services    co-located within the public health system for black South Africans compared    with stand-alone drug treatment facilities. Consequently, introducing and scaling    up the provision of substance-use intervention services in the public health    system may address disparities in access to services.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">These findings    should be interpreted with caution; there was no fidelity monitoring of the    intervention and data were uncontrolled. It remains to be shown whether SBIRT    services can improve medical conditions exacerbated by substance use, alleviate    the abuse of prescription drugs or lower the burden on national healthcare.    Longitudinal studies of hospital-based SBIRT programmes are required for this    purpose.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Nevertheless, our    findings suggest that hospital-based SBIRT holds promise for reducing substance    use and may expand access to care for clients who have historically faced barriers    to drug treatment access. We recommend expanding this pilot programme to other    district hospitals in the Western Cape. Furthermore, we recommend that the centre    expands its services to include strategic screening for substance use throughout    the hospital (e.g. in trauma units), rather than waiting for patient referral.    This could facilitate earlier detection and intervention in substance-related    problems before they become too complex to treat. Furthermore, the centre should    invest in the ongoing monitoring of its services to ensure quality and effectiveness    of care.</font></p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b>Acknowledgements.    </b> We thank and acknowledge the dedication and commitment of the Jooste substance-use    centre team; Maralise van Coller (social worker), Andrit Jeneke (social auxiliary    worker) and ChantalLee Bailey (receptionist). We thank the patients for participating,    the hospital staff and management at Jooste for their support, Dr Hering who    recognised the need for this programme and the Mental Health Programme for their    collaboration with Social Development. This study was funded by the Department    of Social Development of the Western Cape Provincial Government, and managed    by SANCA.</font></p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="3"><b>References</b></font></p>     <!-- ref --><p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">1.&nbsp;Stein DJ,    Seedat S, Herman A, Moomal H, Heeringa SG, Kessler RC, et al Lifetime prevalence    of psychiatric disorders in South Africa. Br J Psychiatry 2008;192(2):112-117.    &#91;<a href="http://dx.doi.org/10.1192/bjp.bp.106.029280" target="_blank">http://dx.doi.org/10.1192/bjp.bp.106.029280</a>&#93;</font>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=548067&pid=S0256-9574201200070002100001&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><!-- ref --><p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">2.&nbsp;Myers B,    Louw J, Pasche S, Inequitable access to substance abuse treatment services in    Cape Town, South Africa. Subst Abuse Treat Prev Policy 2010;5:28. &#91;<a href="http://dx/doi.org/10.1186/1747-597X-5-28" target="_blank">http://dx/doi.org/10.1186/1747-597X-5-28</a>&#93;</font>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=548068&pid=S0256-9574201200070002100002&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><!-- ref --><p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">3.&nbsp;Drummond    C, Coulton S, James D, Godfrey C, Parrott S, Baxter J, et al. Effectiveness    and cost-effectiveness of a stepped care intervention for alcohol use disorders    in primary care: pilot study. Br J Psychiatry 2009;195(5):448-456.</font>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=548069&pid=S0256-9574201200070002100003&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><!-- ref --><p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">4.&nbsp;Babor TFMBG,    Kassebaum PA, Grimaldi PM, Ahmed K, Bray J. Screening, brief, intervention,    and referral to treatment (SBIRT). Subst Abus 2007;28(3):7-30. &#91;<a href="http://dx.doi.org/10.1300/J465v28n03_03" target="_blank">http://dx.doi.org/10.1300/J465v28n03_03</a>&#93;</font>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=548070&pid=S0256-9574201200070002100004&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><!-- ref --><p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">5.&nbsp;WHO ASSIST    Working Group. The alcohol, smoking and substance involvement screening test    (ASSIST): development, reliability and feasibility. Addiction 2002;97(9):1183-1194.    &#91;<a href="http://dx/doi.org/10.1046/j.1360-0443.2002.00185" target="_blank">http://dx/doi.org/10.1046/j.1360-0443.2002.00185</a>&#93;</font>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=548071&pid=S0256-9574201200070002100005&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><!-- ref --><p><font face="Verdana, Arial, Helvetica, sans-serif" size="2">6.&nbsp;Dada S,    Parry C, Pluddemann A, Bhana A, Bachoo S, Fourie D. Alcohol and Drug Abuse Trends:    July - December 2010 (Phase 29) Cape Town: Medical Research Council, 2011.</font>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[&#160;<a href="javascript:void(0);" onclick="javascript: window.open('/scielo.php?script=sci_nlinks&ref=548072&pid=S0256-9574201200070002100006&lng=','','width=640,height=500,resizable=yes,scrollbars=1,menubar=yes,');">Links</a>&#160;]<!-- end-ref --><p>&nbsp;</p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><i>Accepted 9 March    2012.</i></font></p>     <p>&nbsp;</p>     <p>&nbsp;</p>     <p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b><i>Correspondingauthor:    </i></b> <i>K Sorsdahl (<a href="mailto:katherine.sorsdahl@uct.ac.za">katherine.sorsdahl@uct.ac.za</a>)</i></font></p>      ]]></body>
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