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SA Orthopaedic Journal

On-line version ISSN 2309-8309
Print version ISSN 1681-150X

SA orthop. j. vol.8 n.2 Centurion Jan. 2009




Fracture fixation in HIV-positive patients: A literature review



VS Kasipersad

MBChB; Registrar, Department of Orthopaedic Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal




“Full text available only in PDF format”



1. UNAID/WHO. Aids epidemic [update 2007;         [ Links ] cited]; December: [Available from],

2. Cohen B, Piscioneri F, Candido FJ, Rankin KC. Seroprevalence of HIV in orthopaedic patients in Zimbabwe. Journal of Bone & Joint surgery 1994 May;76B.         [ Links ]

3. Bowley DM, Cherry R, Snyman T et al. Seroprevalence of the human immunodeficiency virus in major trauma patients in Johannesburg. South African Medical Journal 2002 Oct;92(10):792-3.         [ Links ]

4. Hoekman P, van de Perre, Nellisen J et al. Increased frequency of infections after open reduction of fractures in patients who are seropositive for human immunodeficiency virus. Journal of Bone and Joint Surgery [Am] 1991 June;73(5):675-9.         [ Links ]

5. Jellis JE. Orthopaedic surgery and HIV disease in Africa. International Orthopaedics 1996;20(4):253-6.         [ Links ]

6. Harrison WJ, Lewis CP, Lavy CB. Wound healing after implant surgery in HIV positive patients. Journal of Bone and Joint Surgery [Br] 2002 Aug;84(6):802-6.         [ Links ]

7. Harrison WJ. HIV/AIDS in trauma and orthopaedic surgery. Journal of Bone and Joint Surgery [Br] 2005 Sep;87(9):1178-81.         [ Links ]

8. Harrison WJ, Lewis CP, Lavy CB. Open fractures of the tibia in HIV positive patients: a prospective controlled single blind study. Injury 2004 Sep;35(9):852-6.         [ Links ]

9. Open Fractures: Principles of Management. Mini Symposium. Current Orthopaedics 1999;13:87-91.         [ Links ]

10. WHO Guidelines on co-trimoxazole prophylaxis for HIV related infections in children, adolescents and adults. Recommendations for a public health approach. 2006.         [ Links ]

11. Richardson J, Hill AM et al. Fracture Healing in HIV-positive populations. Journal of Bone & Joint Surgery 2008;90-B:98-99.         [ Links ]

12. Giannoudis P, Tzioupis C, Talal Almiki et al. Fracture healing in osteoporotic fractures: is it really different? - a basic science perspective. Injury Int J Care Injured 2007;38S1:S90-S99.         [ Links ]

13. Bongiovanni M, Tincati C. Bone diseases associated with Human Immunodeficiency Virus infection: Pathogenesis, risk factors and clinical management. Curr Mol Med 2006 June;6(4):395-400.         [ Links ]

14. Brown P, Crane L. Avascular necrosis of bone in patients with human immunodeficiency virus infection: report of 6 cases and review of the literature. Clinical Infectious Diseases 2001 Apr 15;32(8):1221-6.         [ Links ]

15. Govender S, Harrison W J, Lukhele M. Impact of HIV on bone and joint surgery. Best Practice and Clinical Research Clinical Rheumatology 2008;22(4):605-19.         [ Links ]

16. Harrison WJ, Lavy CB, Lewis CP. One year follow up of orthopaedic implants in HIV positive patients. International orthopaedics 2004 Dec;28(6):329-32.         [ Links ]

17. Brijlall S, Lioma ID and Govender S. Implant sepsis in the HIV infected patient. South African Orthopaedic Journal 2003;2(3):26-30.         [ Links ]

18.Guaraldi G, Ventura P et al. Pathological fractures in AIDS patients with osteopaenia & osteoporosis induced by anti retroviral therapy. AIDS 2001 Jan;15(1):137-8.         [ Links ]

19. Yin MT, Shane E, Anastos K. Clinical significance of HIV-associated bone loss: when & how to intervene. Future HIV 2008;2(5):465-78.         [ Links ]

20. Triant VA, Brown TT et al. Fracture prevalence among HIV- Infected versus non-HIV infected patients in a large US health-care system. Journal of Clinical Endocrinology and Metabolism 2008;93(9):3499-504.         [ Links ]

21. Beveridge M, Howard M. The burden of orthopaedic disease in developing countries. Journal ofBone and Joint Surgery [Am] 2004 Aug;         [ Links ]86A(8):1819-22.

22. Consten EC, van Lanschot JJ et al. A prospective study on the risk of exposure to HIV during surgery in Zambia. AIDS 1995 Jun 9;(6):585-8.         [ Links ]

23. Rowley DI, Clift BA, Sripada S. Surgery in infectious diseases. Current Orthopaedics 2004;18:371.         [ Links ]

24. Hamer AJ, Morris B, Giles M, gillet MG. Aerosol production in orthopaedic theatres - A risk to surgeons? European Journal of Orthopaedic Surgery and Traumatology 1997 Sept;7(3):191-4.         [ Links ]

25. Geberding JL, Little C, Tarkington K, et al. Risk of exposure of surgical personnel to patient's blood during surgery at San Francisco General hospital. N Engl J Med 1990 Jun; 322(25):1788-93.         [ Links ]

26. Centre for Disease Control and Prevention. 1993 Revised Classification System for HIV infection and Expanded Surveillance Case Definition for AIDS among Adolescents and Adults. MMWR 1992;41:1-19.         [ Links ]



VS Kasipersad
Department of Orthopaedic Surgery
University of KwaZulu-Natal
Nelson R Mandela School of Medicine
Private Bag X7
Congella 4013
Tel: (031) 260-4297; Fax: (031) 260-4518



Presented at the Johnson&Johnson Registrar Congress, Durban, February 2009
No benefits of any form have been received from a commercial party related directly or indirectly to the subject of this article.

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