CASE REPORT AND REVIEW OF THE LITERATURE

 

Pathological sacral fracture in type 1 neurofibromatosis

 

 

AW Human^I; Prof S Govender^II

^IMBChB (Pret) Registrar. Head of Department
^IIMBBS, MD, FRCS. Department of Orthopaedic Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal

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INTRODUCTION

Neurofibromatosis (NF) type 1 is one of the most common neurocutaneous disorders. This autosomal dominant genetic disorder is due to an abnormality on chromosome 17¹ that leads to abnormal neural crest cell proliferation. Neurofibromas account for 16-30% of all spinal tumours,² occurring most commonly in the thoracic region, followed by cervical and lumbar region. Only 1-5% occur in the sacral region. We report a sacral fracture due to a neurofibroma in a child with type 1 neurofibromatosis.

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References

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Reprint requests:
Prof S Govender
Department of Orthopaedic Surgery, University of KZN
Nelson R Mandela School of Medicine
Private Bag X7, Congella, 4013
Tel: (031) 260-4297; Fax: (031) 260-4518
E-mail: katia@ukzn.ac.za

 

 

No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. This article is free of plagiarism.