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South African Journal of Chemistry

versión On-line ISSN 1996-840X
versión impresa ISSN 0379-4350

S.Afr.j.chem. (Online) vol.65  Durban  2012

 

RESEARCH ARTICLE

 

GC-MS analysis and antimicrobial activities of the non-polar extracts of Mundulea sericea

 

 

O. MazimbaI, *; I.B. MasesaneI; R.R.T. MajindaI; A. MuzilaII

IDepartment of Chemistry, University of Botswana, Private Bag 0022, Gaborone, Botswana
IIDepartment of Biological Sciences, University of Botswana, Private Bag 0022, Gaborone, Botswana

 

 


ABSTRACT

The composition of the non-polar extracts of the leaves, stem bark and twigs of Mundulea sericea (Fabaceae) were analyzed using GC-MS. Eight, five and eleven components were identified from the leaves, twigs and stem bark extract, respectively. The major components were identified as: caryophyllene (43.6 %) and cadina-3,9-diene (29.7 %) in the leaf extract, amorphene (34.4 %) and valencene (17.9 %) in the stem bark extract and isoledene (29.0 %) and α-gurjunene (22.4 %) from the twig extract. Sesquiterpenes were the major abundant components in the non-polar extracts. The leaf, stem bark and twig extracts showed weak antibacterial and antifungal activities.

Keywords: Mundulea sericea, GC-MS, non-polar, sesquiterpenes, antimicrobial


 

 

Full text available only in PDF format.

 

Acknowledgements

O.M. is grateful to the University of Botswana (Chemistry Department) for the fellowship. The assistance of Mr I. Morobe of the Department of Biological Sciences, University of Botswana during antibacterial testing are gratefully acknowledged.

 

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Received 18 August 2011
Revised 14 September 2011
Accepted 14 February 2012

 

 

* To whom correspondence should be addressed. E-mail: mazimbaof@yahoo.com

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