SHORT COMMUNICATION

Synthesis and characterization of ethyl 2-methyl-7-oxo-7H-isoxazolo[2,3-α]pyrimidine-6-carboxylate derivatives

Ali Khalfallah^*; Mohamed T. Khaddachi

Laboratoire de Chimie Organique, E.S.S.T. Tunis, 5 Avenue Taha Hussein, Montfleury, Tunis 1089, Tunisia

ABSTRACT

Reactions of 5-methylisoxazol-3-amine with diethyl ethoxymethylenemalonate derivatives are described. By this method ethyl 2-methyl-7-oxo-7H-isoxazolo[2,3-a]pyrimidine-6-carboxylate derivatives were prepared and characterized.

Keywords: Isoxazolo[2,3-a]pyrimidine-6-carboxylate, heterocyclic, aminoisoxazole

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Received 22 February 2010
Revised 4 May 2010
Accepted 12 May 2010

* To whom correspondence should be addressed. E-mail: ali.khalfallah@fst.rnu.tn