RESEARCH ARTICLE

 

Simple, efficient and green synthesis of oximes under ultrasound irradiation

 

 

A. Khoramabadi-Zad^*; M. Azadmanesh; A. Rezaee

Faculty of Chemistry, Bu-Ali Sina University, Hamadan 65174, Iran

 

 

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ABSTRACT

The condensation of aldehydes and ketones with hydroxylamine hydrochloride gives oximes in 81-95 % yields in water and EtOH under ultrasound irradiation. Compared to conventional methods, the main advantages of the present procedure are milder reaction conditions, shorter reaction times and higher yields.

Keywords: Condensation, oxime, ultrasonication, aldehydes, ketones

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Acknowledgement

We gratefully acknowledge the support of this work by Bu-Ali Sina University Research Council.

 

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Received 2 August 2010
Revised 19 October
Accepted 1 November 2010

 

 

* To whom correspondence should be addressed. E-mail: khoram@gmail.com