versão On-line ISSN 2078-5135
versão impressa ISSN 0256-9574
SAMJ, S. Afr. med. j. vol.101 no.8 Cape Town Ago. 2011
Evaluation of pain incidence and pain management in a South African paediatric trauma unit
Tessa ThiadensI; Elleke VervatI; Rene AlbertynIII; Monique van DijkII; A B (Sebastian) van AsIV
IDoctorandus. Department of Paediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands
IIPhD. Department of Paediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands
IIIPhD. Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital, Rondebosch, and University of Cape Town
IVA B (Sebastian) van As, MB ChB, MMed, MBA, FCS (SA), PhD. Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital, Rondebosch, and University of Cape Town
OBJECTIVES: To evaluate pain incidence and pain management in a South African paediatric trauma unit, and to compare the usefulness of 5 different assessment tools.
DESIGN: A prospective observational study, using the Numerical Rating Scale for pain (NRS pain), Numerical Rating Scale for anxiety (NRS anxiety), the Alder Hey Triage Pain Score (AHTPS), the COMFORT behaviour scale and the Touch Visual Pain Scale (TVPS). All patients were assessed at admission; those who were hospitalised were again assessed every 3 hours until discharge.
RESULTS: A total of 165 patients, with a mean age of 5.3 years (range 0 - 13), were included. NRS scores were indicative of moderate to severe pain in 13.3% of the patients, and no pain in 24% at admission. Two-thirds of the patients received no analgesics; for them, NRS pain, AHTPS and TVP scores were lower than the scores for the other children.
CONCLUSION: Pain and anxiety incidences in this paediatric trauma unit are relatively low. Implementation of a standard pain assessment tool in the emergency department triage system can improve pain management. The AHTPS is the most promising for use in non-Western settings.
Paediatric trauma patients typically experience pain caused by open wounds, burns and fractures. They may also suffer from distress and emotional pain. Two studies found that management in the Emergency Department (ED) setting was not optimal;1,2 one found that 74% of patients (children and adults) had moderate to severe pain at discharge,2 and the other was a study of pain management practices by nurses in the emergency department (ED) of a large hospital in Rwanda.3 Adult patients presenting to the department in severe pain (visual analogue scale (VAS) scores of 7 or higher) received no analgesic medication until after a median of 150 minutes. The findings mostly pertain to adults, but it seems unlikely that paediatric patients would have more favourable treatment.
Pain assessment in the paediatric ED can be challenging. Since babies and infants are too young to verbalise pain, behavioural pain observations are required to gain insight into the nature and level of pain. Behavioural pain instruments generally are based on facial expression, crying and body movements4,5 and have been validated for different age groups and settings. The Alder Hey Triage Pain Score (AHTPS) was developed specifically for use with children at triage in the accident and emergency (A&E )setting.6 The validity and reliability of these scales in South African ED settings have been little tested.
We aimed to evaluate the pain management and the feasibility of 4 paediatric pain assessment instruments, including the AHTPS, in a South African paediatric trauma unit.
Materials and methods
We conducted a prospective observational study in line with the World Medical Association Declaration of Helsinki. It was approved by the Medical Ethics Committee of the Health Sciences Faculty of the University of Cape Town. We included children aged 0 - 13 years admitted to the trauma unit in the Red Cross War Memorial Children's Hospital (RXCH), which has a dedicated level I trauma unit for children. Patients for whom the attending physician, nurse or parent felt that the study was harmful or too distressing were excluded.
From July to November 2008, 2 medical researchers (TT and EV) who had been trained to reliably assess pain with the selected assessment instruments collected data. Both researchers simultaneously but independently at each measurement moment applied all these 5 instruments in random order. Each eligible child was assessed at triage. If hospitalisation were needed, the assessments were repeated every 3 hours until discharge. Use of analgesics, sedatives and non-pharmacological treatment (distraction, play therapy etc.) was documented at triage at the same time points. Sex, date and time of admission, date and time of discharge, date of birth, type of trauma, type of injury, and procedures were recorded.
The languages most commonly spoken in Cape Town are Afrikaans, English and Xhosa. The researchers were familiar with Afrikaans and English. A Xhosa-speaking nurse explained the study to Xhosa-speaking parents or carers. Before assessing a child, verbal consent was obtained from the attending physician or nurse and from each parent present.
The AHTPS was developed and validated for children aged 0 - 16 years at triage in an A&E setting. Five categories of observations are identified: voice/crying, facial expression, posture, movement and colour. Each of these has a possible score of 0, 1 or 2, resulting in a total score ranging from 0 - 10. Scores >7 are thought to reflect severe pain.6
The COMFORT behaviour scale (COMFORT-B scale) describes 7 behaviours of which only 6 are assessed: of the tandem Crying/ respiratory response, the first applies to spontaneously breathing children, and the second to ventilated children. The items of Alertness, Calmness/agitation, Facial tension, Muscle tone and Body movement apply to all. As responses are on a 1 - 5 Likert scale, with higher score indicating more pain, the total score can range from 6 to 30. Before scoring, the rater observes the patient for 2 minutes. For each item, the score must reflect the most distressed behaviour observed in the 2 minutes. The COMFORT-B scale has been validated for postoperative pain in children up to 3 years old.7 Scores >17 suggest a high risk for pain.
The Touch Visual Pain Scale (TVPS), developed at RXCH, includes a physical examination and observation of body position, facial and body tension, and breathing. The physical examination includes the gentle touching of the patient's feet, ankles, abdomen, chest, hands and arms where muscle tension can be felt and observed. The total score ranges from 0 to 10. Scores >4 require intervention.8
The Numeric Rating Scale (NRS) has been extensively used in clinical and research practice for self-report and observation of pain and anxiety.9,10 It is numbered from 0 to 10, with 0 representing 'no pain /anxiety' and 10 representing 'pain/anxiety as bad as it could be'. The researchers independently and simultaneously applied the NRS both for pain and anxiety. Scores are classified into 3 groups: mild pain (score 1 - 3), moderate pain (score 4 - 6) and severe pain (score 7 - 10).11
The NRS pain and NRS anxiety scores were used to establish criterion validity of the COMFORT-B, TVPS and AHTPS, for pain assessment (AHTPS applied) and pain/anxiety assessment (COMFORT-B and TVPS applied).
Categorical data are presented as frequency (%), whereas continuous data with a normal distribution are presented as mean and standard deviation (SD). Inter-rater reliability was estimated with the intra-class correlation coefficient for continuous variables and with the linearly weighted kappa coefficient for the COMFORT-B items. Coefficients are presented with 95% confidence intervals (CI). The mean scores of both researchers were used in further data analysis.
To determine concurrent validity of COMFORT-B, TVPS and AHTPS, the correlation with NRS pain was determined using Pearson's product moment correlation coefficient. Based on a NRS pain >4, optimal cut-off scores were calculated for the 3 instruments using the best combination of good sensitivity and specificity. In all patients, a maximum of 4 assessments were used to calculate sensitivity and specificity.
Data analysis was performed with SPSS version 15.0 (SPSS Inc, Chicago, IL). For all statistical tests, a significance level of 0.05 was considered statistically significant.
The intra-class correlation coefficient between the 2 researchers was excellent, varying from 0.93 for NRS anxiety to 0.99 for the AHTPS. For the COMFORT-B scale, their kappa coefficient (linearly weighted) was 0.91 for both, based on 14 paired assessments with a qualified nurse.
There were 165 patients; 64.2% were boys, mean age 5 years and 4 months (range 0 - 13 years); 67.3% were discharged within 24 hours (Table I). A total of 205 pain assessments were performed: once in 145 (87.9%) patients, and from 2 - 6 times in the remaining 20 patients. Nearly half (46.7%) of the patients came to the trauma unit without referral from a health care provider; 40.0% of the referred patients came from a day hospital or clinical health centre. The trauma resulted from a fall in 43.6%, and pedestrian involvement in a motor vehicle accident in 21.2%.
Incidence of pain and anxiety
NRS pain scores >4 (moderate to severe) were assigned to 13.3% of the patients; scores of 1 - 3 (minor pain) to 62.7%; and a score of 0 (no pain) to 24%. NRS anxiety scores >4 (moderate to severe) were assigned to 7.1%; scores of 1 -3 (minor anxiety) to 48.9%; and a score of 0 (no anxiety) to 44%.
The AHTPS correlated best with NRS pain (r=0.75). The COMFORT-B scale had the lowest correlation (r=0.55) with NRS pain but the highest correlation with NRS anxiety (r=0.71). The TVPS had a moderate correlation with both NRS pain (r=0.66) and NRS anxiety (r=0.61) (Table II).
With a receiver operating characteristic (ROC) curve based on NRS >4 in 192 assessments, the best ratio between the sensitivity and specificity was found for an AHTPS score >3 (sensitivity 0.95, specificity 0.89). For the COMFORT-B scale, a score >16 resulted in sensitivity of 0.75 and specificity of 0.81. For the TVPS, a score >2 resulted in a sensitivity of 0.83 and a specificity of 0.79 (Fig. 1). The area under the curve (AUC) for AHTP was not statistically significantly different from the AUC of TVP (z=1.19, p=0.23) and AUC of COMFORT-B (z=1.78, p=0.08).
Only 37% of patients received analgesics (Table III); in 6.6%, the prescribed analgesics and sedatives were not, or only partly, given. Children with moderate to severe pain (NRS >4) received analgesics significantly more often (χ2 test 11.13, p=0.001), i.e. 18/31 v. 36/134 of the others (NRS <4).
Of all the patients, 24 (14.5%) received opioids, 37 (22.4%) received paracetamol or paracetamol with codeine, and 6 (3.6%) received a sedative. Of those who received opioids, 10 had been involved in a motor vehicle accident as a pedestrian, and 11 had had falls. At discharge, 15 (9.1%) of all patients were given paracetamol to take home.
Regarding the first pain assessment, the mean NRS pain score for those who afterwards received analgesics was significantly higher than that for those who did not (mean 2.4 (SD 1.8) v. mean 1.5 (SD 1.3) (t-test, p=0.002). Likewise, the mean AHTPS score for those who received analgesics was significantly higher than that for those who did not (mean 2.4 (SD 1.9) v. mean 1.3 (SD 1.3) (t-test, p=<0.001).
Our study showed a low incidence of moderate to severe pain and anxiety in the RXCH paediatric trauma unit. Children with moderate to severe pain received analgesics significantly more often than children with less intense or no pain. The RXCH trauma unit does not apply pain assessment instruments during the triage process.
We compared the use of 5 different pain assessment instruments, using the NRS pain and NRS anxiety as the gold standard. The AHTPS assessment tool appeared to be easy to use and takes little time. Compared with the COMFORT-B scale, the AHTPS 'physical movement' concentrates on the affected body area instead of the whole body, which might be more accurate for use in a trauma unit. Validated cut-off scores for the AHTPS have not been established. Our findings for the ratio between sensitivity and specificity for an AHTPS >3 suggest that score 3 is a good cut-off to differentiate between pain and no pain.
A possible limitation of the COMFORT-B scale in the trauma unit is that it takes approximately 3 minutes to complete, which is long for the ER setting. The TVPS had a moderate correlation with both the NRS pain and the NRS anxiety. As a practical consideration: although touch is an essential part of the TVPS, it was in many cases impossible to touch the patient. The TVPS was originally designed for hospitalised chronically ill infants (e.g. HIV+ infants), which explains why it is not an ideal assessment instrument for the trauma unit, where acute injuries predominate. The overall findings show that the AHTPS, already validated for use in the paediatric A&E department,6 is most promising for developing a pain treatment algorithm.
Some nurses were reluctant to provide opioids since they thought these drugs to be addictive. Other nurses reported that taking pain medication was a sign of weakness and that pain was a logical consequence of injury. Nurses in a hospital in Rwanda felt that cultural factors influenced how they treated pain,3 which is similar to a finding in Australia, providing further indications that assessment of pain in a multi-cultural environment is prone to subjectivities that can conduce to ineffective pain management.12
The question arises whether the true incidence of pain and anxiety was low or whether the instruments used were unsuitable for this particular setting. Possible differences in pain expression between African and Western children might lie in low NRS scores assigned by the two foreign researchers.
A possible limitation of this study is that the nurses were aware of our study topic, which might have encouraged a stricter pain medication administration.
We suggest implementing a combination of the NRS pain scale, NRS anxiety scale and the AHTPS in the ED triage system. Nurses and doctors would be alerted early to a patient's pain and anxiety and so improve pain management. A pain management training module for nursing and medical staff that addresses recognition of pain, pain treatment, and its benefits for the healing process, should be developed. The 2009 guideline of The South African Society of Anaesthesiologists provides information on pain treatment.13 Traditional beliefs and myths about pain and pain treatment should be corrected as an essential factor in further improvement of pain management.
We thank all nurses and doctors from the trauma unit for their support and help with data collection, and Ko Hagoort for editing the manuscript.
The AHTPS chart, TVPS and COMFORT behaviour scale have been included as appendices 1, 2 and 3. The scales are readily available online, and have therefore been excluded from the printed version of this article, but they appear in the online version.
1. Goldman RD, Narula N, Klein-Kremer A, Finkelstein Y, Rogovik AL. Predictors for opioid analgesia administration in children with abdominal pain presenting to the emergency department. Clin J Pain 2008;24(1):11-15. [ Links ]
2. Todd KH, Ducharme J, Choiniere M, et al. Pain in the emergency department: results of the pain and emergency medicine initiative (PEMI) multicenter study. J Pain 2007;8(6):460-466. [ Links ]
3. Rampanjato RM, Florence M, Patrick NC, Finucane BT. Factors influencing pain management by nurses in emergency departments in Central Africa. Emerg Med J 2007;24(7):475-476. [ Links ]
4. Franck LS, Greenberg CS, Stevens B. Pain assessment in infants and children. Pediatr Clin North Am 2000;47(3):487-512. [ Links ]
5. von Baeyer CL, Spagrud LJ. Systematic review of observational (behavioral) measures of pain for children and adolescents aged 3 to 18 years. Pain 2007;127(1-2):140-150. [ Links ]
6. Stewart B, Lancaster G, Lawson J, Williams K, Daly J. Validation of the Alder Hey Triage Pain Score. Arch Dis Child 2004;89(7):625-630. [ Links ]
7. van Dijk M, de Boer JB, Koot HM, Tibboel D, Passchier J, Duivenvoorden HJ. The reliability and validity of the COMFORT scale as a postoperative pain instrument in 0 to 3-year-old infants. Pain 2000;84(2-3):367-377. [ Links ]
8. van Dijk M, Thomas J, Millar A, Tibboel D, Albertyn R, eds. Measuring Pain and Discomfort in HIV+ Infants: Introducing the Touch Visual Pain Scale. Cape Town: The 14th World Congress of Anaesthesiologists, 2008. [ Links ]
9. McCaffery MPC, ed. Pain Clinical Manual. 2nd ed. Maryland, MO: Mosby, 1999. [ Links ]
10. von Baeyer CL, Spagrud LJ, McCormick JC, Choo E, Neville K, Connelly MA. Three new datasets supporting use of the Numerical Rating Scale (NRS-11) for children's self-reports of pain intensity. Pain 2009;143(3):223-227. [ Links ]
11. Krebs EE, Carey TS, Weinberger M. Accuracy of the pain numeric rating scale as a screening test in primary care. J Gen Intern Med 2007;22(10):1453-1458. [ Links ]
12. Fenwick C. Assessing pain across the cultural gap: Central Australian Indigenous peoples' pain assessment. Contemp Nurse 2006;22(2):218-227. [ Links ]
13. The South African Society of Anaesthesiologists. Paediatric guidelines. SAJAA 2009;15(6):37-48. [ Links ]
Accepted 5 May 2011.
Corresponding author: M van Dijk (email@example.com)