On-line version ISSN 2078-5135
SAMJ, S. Afr. med. j. vol.101 n.1 Cape Town Jan. 2011
South African transplantation - where are we now and where should we go next?
To the Editor: South Africa has a huge potential for organ transplantation. Deceased donation is well established, and we are one of the few African countries with brain death legislation. However, despite adequate legislation and well-established transplant units, donor numbers are decreasing and in some areas living donation now outnumbers deceased donation. Saudi Arabia has set an excellent example in utilising deceased donors and is a role model for other Muslim countries in the Middle East and Africa. In a few years they have built up a deceased donation programme and donor numbers are increasing yearly.1
South Africa should strive to provide transplantation leadership and support in the developing world. This requires renewed efforts in obtaining and utilising organ donors. Donation after cardiac death is limited to Groote Schuur Hospital. Consent rates for this type of organ donation are higher in underdeveloped countries, as reflected in increased consent rates at Groote Schuur Hospital. This programme has huge potential, especially in state-sector hospitals where resources to treat head-injured patients are limited.
Factors inhibiting deceased donation from growing in South Africa are religious and social issues, lack of government support (variable organisational systems and variable infrastructure), inappropriate allocation of resources, and a lack of active effort by transplant co-ordinators and doctors in this field. Further obstacles in South Africa are inadequate disease prevention programmes, lack of awareness about brain death diagnosis among health care workers, and lack of funding. Despite a low average income rate in Iran, living and deceased donation is taking place and deceased donation increases yearly.2
In most countries where commercial transplantation took place it had a huge impact on organ transplantation. Deceased donation rates fell dramatically and transplantation for the local population decreased. This is not currently taking place in South Africa, probably because of huge efforts by the Transplantation Society and the Istanbul Declaration Custodian Group.3 This continuing worldwide problem warrants constant attention.
Liver transplantation in South Africa is limited to deceased donor liver transplantation. Turkey, Egypt and Iran have active living related liver transplantation programmes, and most transplants are done for paediatric recipients. There is no living related liver transplant programme in South Africa, despite a favourable recipient pool at Red Cross War Memorial Children's Hospital.
South Africa must compare itself to other developing countries regarding organ donation and transplantation. We cannot compete with the developed world in terms of infrastructure, support and funding. However, transplant surgeons and physicians must renew efforts to establish and preserve these programmes in the state and private sectors. It is important that continuous efforts be made to increase our deceased donation rates to serve the population awaiting organs.
Groote Schuur Hospital
1. Atter B, Shaheen F, Souqiyyeh MZ, et al. The experience of expanded criteria donors in kidney transplantation in Saudi Arabia: 2008-9. Oral presentation, MESOT congress, Tunisia, 18-21 October 2010. [ Links ]
2. Ghornai F, Vishteh HRK, Shafaghi S, et al. Brain death training for hospital workers increase donor detection rate. Oral presentation, MESOT congress, Tunisia, 18-21 October 2010. [ Links ]