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South African Journal of Surgery

On-line version ISSN 2078-5151
Print version ISSN 0038-2361

S. Afr. j. surg. vol.48 n.4 Cape Town Nov. 2010




One-stage excision of inflamed sebaceous cyst versus the conventional method



Ge Bu JunI; Huang QiI; Chanseet GolapII

Im.D.; Department of General Surgery, Tongji Hospital and Tongji University, Shanghai, People's Republic of China
IIm.b. B.S. (postgraduate student, general surgery, final year); Department of General Surgery, Tongji Hospital and Tongji University, Shanghai, People's Republic of China



OBJECTIVE: The aim of this trial was to determine whether one-stage excision of inflamed sebaceous cysts is preferable to the conventional method.
METHODS: A group of 166 patients underwent primary resection of an inflamed sebaceous cyst followed by 5 days' administration of antibiotics. A further 185 patients underwent conventional treatment consisting of initial antibiotic administration and incision and drainage of the lesion, followed by elective surgical excision 1 - 2 months later when the inflammation had subsided. Duration of antibiotic exposure, morbidity and cost were compared between the two groups.
RESULTS: One-stage excision of inflamed sebaceous cysts decreased the duration of antibiotic exposure, reduced morbidity and is more economical.
CONCLUSION: This study strongly suggests that, provided cases are appropriately selected, primary resection of inflamed sebaceous cysts has advantages over conventional treatment.


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1. Brook I. Microbiology of infected epidermal cysts. Arch Dermatol 1989; 125: 1658-1661.         [ Links ]

2. Diven DG, Dozier SE, Meyer DJ, Smith EB. Bacteriology of inflamed and uninflamed epidermal inclusion cyst. Arch Dermatol 1998; 134(1): 49-51.         [ Links ]

3. Camidge DR, Matheson LM. Cutaneous B lymphoma arising from a chronically inflamed sebaceous cyst. Lancet Oncol 2000; 1(1): 24-24.         [ Links ]

4. Sharma H, Sinha A, Singh BJ. Sebaceous cyst presenting with necrotizing ulcerative infection over trochanteric area mimicking necrotizing fascitis. Journal of the European Academy of Dermatology and Venerology 2006; 20(3): 345- 346.         [ Links ]

5. Poonawalla T, Vchida T, Diven DG. Survey of antibiotic prescription use for inflamed epidermal inclusion cysts. J Cutan Med Surg 2006; 10(22): 79-84.         [ Links ]

6. Kuniyuki S, Yoshida Y, Maekawa N, Yamanaka K. Bacteriological study of epidermal cysts. Acta Derm Venereol 2008; 88: 23-25.         [ Links ]

7. Khafif RA, Attie JN. One stage excision of infected sebaceous cyst. Arch Surg 1969; 98: 117-118.         [ Links ]

8. Kitamura K, Takahashi T, Yamagushi T, Shimotuma M, Majima T. Primary resection of infectious epidermal cyst. J Am Coll Surg 1994 Nov; 179(5): 607-608.         [ Links ]

9. Goldstein BG, Goldstein AO. Benign neoplasms of the skin. Up To Date (online database). Updated 21 Nov 2005. (accessed 1 April 2009).         [ Links ]

10. Culver DH, Horan TC, Gaynes RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index. National Nosocomial Infections Surveillance System. Am J Med 1991; 91(3B): 152S-157S.         [ Links ]

11. Gottrup F, Melling A, Hollander DA. An overview of surgical site infections: aetiology, incidence and risk factors. World Wide Wounds Sep 2005. (accessed 1 April 2009).         [ Links ]

12. Miyata T, Torisu M. A new surgical approach for treating infected epidermoid cysts using delayed primary closure. Jpn J Surg 1989; 19: 532534.         [ Links ]

13. El Al Ami M, Ghufoor K, Dilkes M. Laser marsipulization of epidermal cysts: avoiding linear scars. J Clin Laser Med Surg 2003; 21: 161-163.         [ Links ]

14. Zuber TJ. Minimal excision technique for epidermoid (sebaceous) cysts. Am Fam Physician 2002; 65: 1409-1412, 1417-1418, 1420.         [ Links ]

15. Moore RB, Fagan EB, Hulkower S, Skolnik DC, O'Sullivan G. What's the best treatment for sebaceous cysts? J Fam Pract 2007; 56(4): 315-316.         [ Links ]

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