Abstract

GOBUSAMANG, Ellen; NYEPETSI, Naledi G.; MOTSWALEDI, Modisa S.  and  KASVOSVE, Ishmael. Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana. Afr. J. Lab. Med. [online]. 2019, vol.8, n.1, pp.1-4. ISSN 2225-2010.  http://dx.doi.org/10.4102/ajlm.v8i1.722.

Medical records and residual samples from 334 type 2 diabetes mellitus patients attending a clinic in Gaborone, Botswana, during the period September-December 2016 were analysed for the effects of hyperuricaemia on biochemical markers of adverse outcomes. The patients were stratified as having hyperuricaemia (> 400 µmol/L) or normal serum uric acid (≤ 400 µmol/L). We compared glycated haemoglobin, triglycerides, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, total cholesterol and serum creatinine between the two serum uric acid categories. Hyperuricaemia was detected in 28% of patients (95% confidence interval 23.1-32.9) and was associated with increased serum triglycerides, triglyceride to high-density lipoprotein-cholesterol ratio and creatinine concentration, but not with glycated haemoglobin.

Keywords : hyperuricaemia; diabetes mellitus; glycated haemoglobin; lipids; Africans.

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