Abstract

MOTSWALEDI, Modisa S.; KASVOSVE, Ishmael  and  OGUNTIBEJU, Oluwafemi O.. Potential role of Lu/BCAM in HIV-related atherosclerosis. Afr. J. Lab. Med. [online]. 2019, vol.8, n.1, pp.1-4. ISSN 2225-2010.  http://dx.doi.org/10.4102/ajlm.v8i1.792.

Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients.

Keywords : cholesterol; Non-high-density lipoprotein cholesterol; Lu [BCAM]; Atherosclerosis.

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