Abstract

ROOS, Johannes L.  and  KOTZE, Carla. Early deviant behaviour as a dimension trait and endophenotype in schizophrenia. S. Afr. j. psyc. [online]. 2022, vol.28, n.1, pp.1-6. ISSN 2078-6786.  http://dx.doi.org/10.4102/sajpsychiatry.v28i0.1747.

BACKGROUND: In psychiatry, there is still a lack of objective biological diagnostic measurements. It is important to investigate measurements or symptom dimensions that can inform diagnostic assessments and allow for a more personalised approach to patients AIM: To discuss how early deviant behaviour (EDB) may be seen as a possible continuous symptom dimension trait and endophenotype in schizophrenia METHODS: Conducting a commentary review by highlighting some important findings from available literature RESULTS: Findings regarding EDB in schizophrenia in a South African genetic sample point towards EDB as a progressive subtype of schizophrenia, with very early onset of illness (even prior to the psychotic symptomatology) and a genetic form of illness CONCLUSION: Valuable information can be gained by enquiring into EDB and viewing it as a continuous symptom dimension trait and endophenotype during the psychiatric diagnostic interview

Keywords : early onset; deviant behaviour; schizophrenia; endophenotype; continuous symptom dimension.

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