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SA Journal of Radiology
versión On-line ISSN 2078-6778
versión impresa ISSN 1027-202X
Resumen
SHERWANI, Poonam; NANDOLIA, Khanak K.; JOSHI, Kirti y LOUREMBAM, Radhapyari. Imaging in Van Wyk Grumbach syndrome: An uncommon presentation of hypothyroidism. S. Afr. J. radiol. (Online) [online]. 2023, vol.27, n.1, pp.1-4. ISSN 2078-6778. http://dx.doi.org/10.4102/sajr.v27i1.2572.
Isosexual precocious puberty with ovarian masses in long-standing juvenile hypothyroidism is well described in the literature as Van Wyk Grumbach syndrome (VWGS). The present case reports this rare entity in a 4-year-old girl who was referred for imaging to evaluate the cause of non-traumatic bleeding per vagina. Antecedent history, clinical features and thyroid function tests were consistent with long-standing juvenile hypothyroidism with documented clinical response to thyroxine replacement therapy. CONTRIBUTION: Typical clinical and radiological features of the syndrome are reported, which helps in the early diagnosis and management, henceforth avoiding the associated complications.
Palabras clave : galactorrhoea; hypothyroidism; isosexual precocious puberty; pituitary; ovarian mass; thyroid stimulating hormone (TSH); per vagina; Van Wyk Grumbach syndrome (VWGS).