Services on Demand
Article
Indicators
Related links
- Cited by Google
- Similars in Google
Share
SA Journal of Radiology
On-line version ISSN 2078-6778
Print version ISSN 1027-202X
Abstract
ZAFAR, Sara; JAVED, Maria; ROCKWOOD, Neesha and KAZMI, Farhat. Primary central nervous system lymphoma presenting as multiple space-occupying lesions in advanced human immunodeficiency virus infection. S. Afr. J. radiol. (Online) [online]. 2017, vol.21, n.2, pp.1-6. ISSN 2078-6778. http://dx.doi.org/10.4102/sajr.v21i2.1234.
A 31-year-old man presented with seizures and cerebellar symptoms on a background of weight loss and lethargy. He was found to be infected with human immunodeficiency virus (HIV) and following radiological imaging, was commenced on treatment for presumed cerebral toxoplasmosis. Due to a lack of response, both clinically and on interval imaging, a positron-emission tomography-computed tomography and brain biopsy were undertaken, which demonstrated high-grade primary central nervous system lymphoma (PCNSL). Awareness amongst both clinicians and radiologists of the multifarious patterns of intra-cranial involvement in patients with HIV is, therefore, of utmost importance, as the treatment and prognosis of these entities are entirely different.