Abstract

PHOLOGOLO, Thabo et al. The prevalence of cervical abnormalities: Comparison of youth with perinatally acquired HIV and older women in Botswana. South. Afr. j. HIV med. (Online) [online]. 2023, vol.24, n.1, pp.1-5. ISSN 2078-6751.  http://dx.doi.org/10.4102/sajhivmed.v24i1.1455.

BACKGROUND: Cervical cancer burden and prevalence of precursor lesions is unknown among young women living with HIV in high prevalence settings. Current cervical cancer screening guidelines in resource-limited settings with high HIV prevalence typically exclude adolescents and young women. After observing two cases of advanced cervical cancer among young women with perinatally acquired HIV, a pilot screening programme was established in Botswana. OBJECTIVES: To compare the prevalence of cervical abnormalities in young women with perinatally acquired HIV with women aged 30-49 years, regardless of HIV status. METHOD: We conducted a cross-sectional study of 30-49-year-old women who had visual inspection with acetic acid screening through the Botswana public sector programme, and youth (aged 15-24 years) with perinatally acquired HIV, at a single referral site between 2016 and 2018. We describe the prevalence of cervical abnormalities in each group as well as the crude prevalence ratio. RESULTS: The prevalence of cervical abnormalities in women 30-49 years of age was 10.9% (95% confidence interval [CI]: 10.4, 11.4), and 10.1% (95% CI: 4.7, 18.3) for youth. The crude prevalence ratio was 1.07 (95% CI: 0.58, 2.01). CONCLUSION: Inclusion of youth living with HIV in cervical cancer screening services should be considered in settings with a high prevalence of HIV and cervical cancer.

Keywords : perinatal HIV; young women; visual inspection with acetic acid; cervical cancer screening; Africa.

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