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South African Journal of Child Health

versión On-line ISSN 1999-7671
versión impresa ISSN 1994-3032

Resumen

KRYNAUW, R; DU PREEZ, J C F; VAN ZYL, J I  y  BURGER, M. The trajectory of general movements from birth until 12-14 weeks corrected age in very low-birthweight and extremely low-birthweight infants born preterm. S. Afr. j. child health [online]. 2022, vol.16, n.2, pp.99-104. ISSN 1999-7671.  http://dx.doi.org/10.7196/sajch.2022.v16i2.1893.

BACKGROUND: General movement assessment (GMA) is an assessment tool with high predictive validity for neurodevelopmental outcomes in preterm infants. Information available describing the trajectory of general movements (GMs) in high-risk preterm-born infants and the use thereof in low- and middle-income countries is limited OBJECTIVE: To describe the trajectories of GMs from birth until 12 - 14 weeks' corrected age, and determine the association of known perinatal risk factors on GM trajectories in very low-birthweight and extremely low-birthweight preterm infants METHODS: This was a longitudinal, prospective cohort study with 119 preterm infants born at <33 weeks' gestation and with a birthweight <1 500 g. GMs were recorded at four key age periods: 1-2 weeks after birth to 33 weeks post menstrual age (PMA); 34 - 37 weeks PMA; term equivalent age (TEA); and 12 - 14 weeks corrected age. Detailed perinatal data were collected RESULTS: A total of 300 GMAs were conducted, 157 during the preterm age, 55 during TEA and 88 at 12 - 14 weeks corrected age. At <33 weeks PMA, 96% of GMs were abnormal and 4% normal. At 34 - 37 weeks PMA, 89% of GMs were abnormal and 11% normal. All GMs recorded at term equivalent age were abnormal. At 12 - 14 weeks corrected age, 7% of GMs were abnormal and 93% normal CONCLUSION: GMs were predominantly abnormal prior to term with a significant decrease in abnormality at 12 - 14 weeks corrected age. Lower birthweight and lower PMA were associated with increased odds for abnormal GMs. In a resource-constrained environment, observing GMs at 12 - 14 weeks corrected age (during the fidgety period) is a time- and cost-effective method to determine the risk for adverse neuro development

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