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South African Journal of Child Health
On-line version ISSN 1999-7671
Print version ISSN 1994-3032
Abstract
PADAYACHI, T and HAFFEJEE, I E. Too much diarrhoea, too many infections, and too few neutrophils. S. Afr. j. child health [online]. 2016, vol.10, n.1, pp.96-98. ISSN 1999-7671. http://dx.doi.org/10.7196/sajch.2016.v10i1.1050.
Neutropenia is a common finding in ill paediatric patients and can be conveniently subdivided into that due to decreased production or increased destruction. Intrinsic defects in granulocytes or their progenitors or extrinsic factors such as infection, drugs and autoimmune phenomena are the main causes. Our case focuses on cyclic neutropenia presenting with severe chronic diarrhoea lasting 17 weeks, multiple recurrent bacterial infections and pulmonary tuberculosis (TB). To our knowledge this is the first case of pulmonary TB described in association with cyclic neutropenia and chronic diarrhoea in Africa.