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SA Orthopaedic Journal

On-line version ISSN 2309-8309
Print version ISSN 1681-150X


RASOOL, MN  and  GENZENGANE, V. Rosai-Dorfman disease of the distal radius in a child: A case report and review of the literature. SA orthop. j. [online]. 2015, vol.14, n.4, pp.67-70. ISSN 2309-8309.

Rosai-Dorfman disease (RDD) is a non-neoplastic self-limiting disease of bone marrow stem cell origin characterised by cervical lymphadenopathy. Primary osseous lesions are rare and the condition can mimic various solitary bone lesions radiologically. A 15-month-old child presented with an isolated, well-defined, lucent lesion of the distal radius. Histology demonstrated numerous large histiocytes with intracytoplasmic lymphocytes, plasma cells and neutrophils. Immunohistochemistry showed CD 68 immunopositivity, confirming RDD. Healing of the lesion was seen 6 months post-operatively following curettage. Isolated extranodal osseous lesions are very rare in children and can mimic several osseous conditions.

Keywords : Rosai-Dorfman disease; distal radius; emperipolesis.

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