SciELO - Scientific Electronic Library Online

 
vol.14 issue4Expanding the orthopaedic training programme to improve the management of lower extremity traumaSubclinical hypoperfusion in trauma patients and its influence on surgical fracture fixation: Systematic review and meta-analysis author indexsubject indexarticles search
Home Pagealphabetic serial listing  

SA Orthopaedic Journal

On-line version ISSN 2309-8309

Abstract

RAUBENHEIMER, EJ  and  HENDRIK, HD. Cell signalling and bone remodelling: The skeleton as an endocrine relay organ - Part 1. SA orthop. j. [online]. 2015, vol.14, n.4, pp. 16-21. ISSN 2309-8309.  http://dx.doi.org/10.17159/2309-8309/2015/v14n4a1.

As knowledge on the signalling pathways involved in bone remodelling unfolds, maintenance of skeletal health and the management of skeletal diseases will increasingly focus on the manipulation of the autocrine, paracrine and endocrine mechanisms involved in the process. This overview is aimed at providing practitioners with an update on recent advances on cell signalling in bone remodelling and highlights the role of the skeleton in systemic metabolism.

Keywords : bone metabolism; cell signalling; skeletal remodelling.

        · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License