SA Orthopaedic Journal
Print version ISSN 1681-150X
Thirty consecutive cases of osteosarcoma treated over a five-year period were reviewed retrospectively. The cases were notable for the advanced stage of disease at presentation with half the patients presenting with metastases, and unusually large mean tumour sizes. The majority of patients needed amputation for local control of the tumour. Although follow-up is short, a third of the patients are disease-free at a mean of 30 months and a sixth alive with metastases at a mean of 16 months. Half the patients are presumed or known to be dead. Presence of metastases at diagnosis and size greater than 10 cm were associated with a poor prognosis.
Keywords : osteosarcoma; outcomes; South Africa.