SA Orthopaedic Journal
versão On-line ISSN 2309-8309
versão impressa ISSN 1681-150X
Awareness of the importance of skin exposure to UV rays for normal bone growth and systemic health increased with landmark scientific discoveries over the past century. Several Nobel-prize laureates unravelled the steps involved in the activation of 7-dehydrocholesterol to 1,25 (OH)2 vitamin D (or vit D3) which is rapidly becoming the most important medical discovery in the past decade. Recent developments in our understanding of the impact of vit D on the immune system, carbohydrate metabolism, and cardiovascular and neoplastic diseases are briefly highlighted.
Palavras-chave : vitamin D; cholecalciferol; ergocalciferol; phototherapy; UV light.