SA Orthopaedic Journal
versão On-line ISSN 2309-8309
versão impressa ISSN 1681-150X
RAUBENHEIMER, EJ. Part II: Metabolic bone disease: Recent developments in the pathogenesis of rickets, osteomalacia and age-related osteoporosis. SA orthop. j. [online]. 2009, vol.8, n.1, pp.38-42. ISSN 2309-8309.
The term 'metabolic bone disease' encompasses an unrelated group of systemic conditions that impact on skeletal collagen and mineral metabolism. Their asymptomatic progression leads to advanced skeletal debilitation and late clinical manifestation. This article provides a brief overview of advances in the understanding of the pathogenesis of rickets, osteomalacia and age-related osteoporosis.