Journal of the South African Veterinary Association
On-line version ISSN 2224-9435
BOTHA, Christo J.. Krimpsiekte in South Africa: Historical perspectives. J. S. Afr. Vet. Assoc. [online]. 2013, vol.84, n.1, pp. 1-5. ISSN 2224-9435.
Krimpsiekte, also known as cotyledonosis or nenta in sheep and goats, has been recognised as a disease entity since 1775. However, it was only in 1891 that Veterinary Surgeon Soga reproduced the condition by dosing Cotyledon (= Tylecodon) ventricosus leaves to goats. Professor MacOwan, a botanist, confirmed the identity of these nenta plants. From a South African veterinary toxicological point of view the date 1891 is of considerable historical significance as this was the first time that a plant was experimentally demonstrated to be toxic to livestock in South Africa. A chronological account of the history of krimpsiekte research is provided.