Journal of the South African Veterinary Association
On-line version ISSN 2224-9435
Print version ISSN 1019-9128
LE ROUX-PULLEN, L and LESSING, D. Should veterinarians consider acrylamide that potentially occurs in starch-rich foodstuffs as a neurotoxin in dogs?. J. S. Afr. Vet. Assoc. [online]. 2011, vol.82, n.2, pp.129-130. ISSN 2224-9435.
Three clinically healthy Labrador puppies developed ataxia, hypermetria and convulsions shortly after eating the burnt crust of maize porridge. Two of the puppies died. Acrylamide toxicity was considered based on the history of all 3 puppies developing nervous signs after being exposed to a starch-based foodstuff that was subjected to high temperature during preparation. Acrylamide-induced neurotoxicity is thought to partially result from a distal axonopathy.
Keywords : acrylamide; ataxia; convulsions; distal axonopathy; high temperature; hypermetria; starch.