Journal of the South African Veterinary Association
On-line version ISSN 2224-9435
JOUBERT, K E et al. Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris). J. S. Afr. Vet. Assoc. [online]. 2011, vol.82, n.2, pp. 94-96. ISSN 2224-9435.
The optimal dose of medetomidine-ketamine-buprenorphine was determined in 25 Cape ground squirrels (Xerus inauris) undergoing surgical implantation of a temperature logger into the abdominal cavity. At the end of anaesthesia, the squirrels were given atipamezole intramuscularly to reverse the effects of medetomidine. The mean dose of medetomidine was 67.6 ± 9.2 µg/kg, ketamine 13.6 ± 1.9 mg/kg and buprenorphine 0.5 ± 0.06 µg/kg. Induction time was 3.1 ± 1.4 min. This produced surgical anaesthesia for 21± 4.2 min. Atipamezole 232 ± 92 µg/kg produced a rapid recovery. Squirrels were sternally recumbent in 3.5 ± 2.2 min.
Keywords : anaesthesia; atipamezole; buprenorphine; Cape ground squirrel; ketamine; medetomidine; Xerus inauris.