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South African Journal of Chemistry

On-line version ISSN 1996-840X
Print version ISSN 0379-4350

Abstract

YANG, Chengcheng et al. Highly Sensitive Electrochemical Sensing Platform for the Detection of L-dopa Based on Electropolymerizing Glutathione Disulfide and Multi-walled Carbon Nanotube-modified Electrodes. S.Afr.j.chem. (Online) [online]. 2018, vol.71, pp.182-187. ISSN 1996-840X.  http://dx.doi.org/10.17159/0379-4350/2018/v71a24.

A facile sensing platform for the detection of L-dopa has been developed by electropolymerizing glutathione disulfide (PGSSG) on the surface of glass carbon electrodes (GCE) which were modified by multi-walled carbon nanotubes (MWCNTs). The electrochemical behaviour of the proposed electrodes were investigated via cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The morphology of the PGSSG and PGSSG/MWCNTs were characterized by scanning electron microscopy (SEM). Under the optimized experimental conditions, the sensing platform showed the linear response to L-Dopa in a range from 1.0 X 10-6 to 1.2X10-3 M with a detection limit of 3.3 X 10-7 M (S/N = 3). Moreover, with the merits of high sensitivity and selectivity, good stability and reproducibility, the sensor was successfully applied for the determination of L-dopa in a real sample.

Keywords : L-dopa; glutathione disulfide; multi-walled carbon nanotubes; electropolymerization; electrochemical determination.

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