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South African Journal of Chemistry

versão On-line ISSN 1996-840X
versão impressa ISSN 0379-4350


KHODABAKHSHI, Saeed; KARAMI, Bahador; ESKANDARI, Khalil  e  RASHIDI, Alimorad. A facile and practical p-Toluenesulfonic acid catalyzed route to dicoumarols containing an Aroyl group. S.Afr.j.chem. (Online) [online]. 2015, vol.68, pp.53-56. ISSN 1996-840X.

New and known dicoumarols may be efficiently synthesized employing p-toluenesulfonic acid (p-TSA) as a solid acid catalyst from the reaction of 4-hydroxycoumarin with aryl glyoxal in water. This method offers direct access to structurally diverse coumarin derivatives in moderate to good yields (up to 65%). A total of five new compounds were synthesized.

Palavras-chave : Dicoumarol; p-toluenesulfonic acid; aryl glyoxal; 4-hydroxycoumarin.

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