South African Journal of Chemistry
On-line version ISSN 1996-840X
Print version ISSN 0379-4350
KARAMI, Bahador; FARAHI, Mahnaz; BAZRAFSHAN, Masoomeh and KHODABAKHSHI, Saeed. Silica-Supported Yttrium Nitrate Hexahydrate as a Heterogeneous Catalyst for the Synthesis of 2-Amino-4H-Chromenes in Water. S.Afr.j.chem. (Online) [online]. 2014, vol.67. ISSN 1996-840X.
Silica-supported yttrium nitrate hexahydrate (Y(NO3)3.6H2O/SiO2) has been found to be an efficient and reusable catalyst for the synthesis of 2-amino-4H-chromenes via a one-pot aqueous three-component reaction between arylaldehydes, malononitrile and ß-naphthol in high yields. This method has many appealing attributes such as excellent yields, short reactions time, reusability of the catalyst and simple work-up procedure.
Keywords : Silica-supported yttrium nitrate hexahydrate; 2-amino-4H-chromene; malononitrile; arylaldehyde; ß-naphthol.