South African Journal of Chemistry
On-line version ISSN 1996-840X
Print version ISSN 0379-4350
KHORRAMABADI-ZAD, Ahmad; AZADMANESH, Mohammad and MOHAMMADI, Somaye. One-Pot, Simple and Efficient Synthesis of Triaryl-1H-imidazoles by KMnO4/CuSO4. S.Afr.j.chem. (Online) [online]. 2013, vol.66, pp.239-247. ISSN 1996-840X.
2,4,5-Triarylimidazoles have been obtained in excellent yields by the one-pot three-component condensation of bis-aryl a-hydroxyketones, aromatic aldehydes and ammonium acetate by the action of inexpensive, readily available and nontoxic KMnO4/CuSO4 under mild reaction conditions. The present method is simple, efficient, cost-effective and eco-friendly.
Keywords : Triarylimidazoles; Three-component reaction; One-pot synthesis; Oxidation; bis-aryl a-hydroxyketone; KMnO4; CuSO4.