South African Journal of Chemistry
On-line version ISSN 1996-840X
SETAMDIDEH, Davood and KHALEDI, Leila. Zn(BH4)2/2NaCl: A novel reducing system for efficient reduction of organic carbonyl compounds to their corresponding alcohols. S.Afr.j.chem. (Online) [online]. 2013, vol.66, pp. 00-00. ISSN 1996-840X.
Zn(BH4)2/2NaCl, obtained by the reaction of ZnCl2 and NaBH4 ,is a stable, efficient and selective reducing system in dry-THF. The Zn(BH4)2/2NaCl system (0.5-1 mmol) reduces a variety of carbonyl compounds to their corresponding alcohols in CH3CN at room temperature in high to excellent yields.
Keywords : Reduction; carbonyl compounds; Zn(BH4)2; chemoselective; regioselectivity; NaCl.