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South African Journal of Chemistry

On-line version ISSN 1996-840X
Print version ISSN 0379-4350


EBRAHIMI, Sattar. Synthesis of novel bibrachial lariat ethers (BiBLEs) containing [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines. S.Afr.j.chem. (Online) [online]. 2013, vol.66, pp.00-00. ISSN 1996-840X.

A practical and regioselective method for the synthesis of cis-diastereomers of bibrachial lariat ethers (BiBLEs) bearing ester and amide groups is reported. The novel bibrachial lariat ethers (BiBLEs) 3a-d with neutral side chains were preparedby reaction of the corresponding aza-crown macrocycles 1a-b with ethyl chloroacetate and chloroacetamide.

Keywords : macrocycle; bibrachial; lariat ethers; aza-crown; 1,3,4-thiadiazines.

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