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South African Journal of Chemistry

On-line version ISSN 1996-840X
Print version ISSN 0379-4350


KARAALI, Nesrin et al. Microwave-assisted synthesis of some 1H-1,2,4-triazol-3-one derivatives. S.Afr.j.chem. (Online) [online]. 2013, vol.66, pp.00-00. ISSN 1996-840X.

4-Amino-5-(methyl/ethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one were synthesized from the reaction of (methyl/ethyl)-ester ethoxycarbonyl hydrazone with hydrazine hydrate and then, converted to corresponding Schiff bases using 9H-fluorene-3-carbaldehyde. Ester, hydrazide and oxadiazole derivatives were synthesized starting from Schiff bases in three steps. All reactions occurred under conventional conditions and microwave irradiation. The obtained results were compared.

Keywords : Triazole; oxadiazole; hydrazine hydrate; microwave irradiation.

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