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South African Journal of Chemistry

On-line version ISSN 1996-840X

Abstract

NXUMALO, Winston  and  DINSMORE, Andrew. Negishi coupling of pteridine-O-sulfonates. S.Afr.j.chem. (Online) [online]. 2013, vol.66, pp. 00-00. ISSN 1996-840X.

Negishi coupling of pteridine-O-sulfonate with Zn-aryls is reported. Hydrolysis of the protecting groups with 1M NH3 gave the 6-subustituted 2,4-diaminopteridine while hydrolysis with 1 M NaOH gave the 6-subsituted pterin.

Keywords : Pteridine; pterin; Negishi coupling.

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