South African Journal of Chemistry
versão On-line ISSN 1996-840X
YELWANDE, Ajeet A. et al. SnO2/SiO2 nanocomposite catalyzed one-pot, four-component synthesis of 2-amino-3-cyanopyridines. S.Afr.j.chem. (Online) [online]. 2012, vol.65, pp. 131-137. ISSN 1996-840X.
An efficient and rapid protocol for the synthesis of 2-amino-3-cyanopyridines by the cyclocondensation reaction of aromatic aldehydes, methyl ketones, malononitrile and ammonium acetate catalyzed by SnO2/SiO2 nanocomposite material at refluxed condition in ethanol was investigated. Nanocomposite (SnO2/SiO2) catalytic material has been synthesized by using the sol-gel method. The prepared catalytic materials were characterized by using X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR), Brunauer-Emmer-Teller (BET) surface area, and temperature-programmed desorption of ammonia (NH3-TPD). Advantages of the present method include a simple work-up procedure, high yields of the products, low toxicity and easy recovery and reusability of the catalytic materials.
Palavras-chave : SnO2/SiO2; sol-gel; nanocomposite; 2-amino-3-cyanopyridines; heterogeneous catalyst.