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South African Journal of Chemistry

versão On-line ISSN 1996-840X

Resumo

KARIMI-JABERI, Zahed  e  ZAREI, Leila. Rapid synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones using boric acid or sodium dihydrogen phosphate under solvent-free conditions. S.Afr.j.chem. (Online) [online]. 2012, vol.65, pp. 36-38. ISSN 1996-840X.

Two efficient and convenient methods have been described for synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinone derivatives by one-pot condensation of 2-anthranilamide with aldehydes or ketones in the presence of a catalytic amount of boric acid or sodium dihydrogen phosphate under solvent-free conditions. The attractive features of these processes are short reaction times, easy isolation of products, excellent yields and an environmental friendly procedure.

Palavras-chave : Dihydroquinazolinones; boric acid; sodium dihydrogen phosphate; 2-anthranilamide; solvent-free synthesis.

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