SciELO - Scientific Electronic Library Online

vol.64Synthesis, characterization and application of nano lepidocrocite and magnetite in the degradation of carbon tetrachlorideHigh school Physical Sciences teachers' competence in some basic cognitive skills author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand



Related links

  • On index processCited by Google
  • On index processSimilars in Google


South African Journal of Chemistry

On-line version ISSN 1996-840X
Print version ISSN 0379-4350


RAMOS, Josierika A. Ferreira; NAGEM, Tanus J.  and  TAYLOR, Jason G.. Expedient access to an N-phenylpyrrolidin-2-yl heterocycle via a base-induced intramolecular aza-Michael reaction. S.Afr.j.chem. (Online) [online]. 2011, vol.64, pp.225-230. ISSN 1996-840X.

Ethyl 2-(1-phenylpiperidin-2-yl) acetate was formed in a spontaneous cyclization from (E)-ethyl 7-oxohept-2-enoate whereas ethyl [1-(2-bromophenyl)-2-pyrrolidinyl acetate could be synthesized in good overall yield when employing a stoichiometric amount of base to facilitate the intramolecular aza-Michael reaction.

Keywords : aza Michael; intramolecular; catalysed; piperidine; pyrrolidine; base.

        · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License