SciELO - Scientific Electronic Library Online

 
vol.63Simple, efficient and green synthesis of oximes under ultrasound irradiationPolyaniline/SiO2 catalyzed one-pot synthesis of tetrahydrobenzo[b]pyran derivatives índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Em processo de indexaçãoSimilares em Google

Compartilhar


South African Journal of Chemistry

versão On-line ISSN 1996-840X

Resumo

KAWTHEKAR, Rahul B. et al. Synthesis of (S)-3-aminoethyl-1,2,3,4-tetrahydroisoquinoline (TIQ-diamine) via the Mitsunobu protocol. S.Afr.j.chem. (Online) [online]. 2010, vol.63, pp. 195-198. ISSN 1996-840X.

The synthesis of (S)-3-Aminoethyl-1,2,3,4-tetrahydroisoquinoline (TIQ-diamine) was successfully achieved via the Mitsunobu protocol. The method from earlier reports utilizing aminolysis of commercially available TIQ-amino methyl ester, and reduction of the amide, proved to be inadequate for preparation of TIQ-diamines. The modified route requires three additional steps and consequently rendered three novel intermediates, which were furnished under mild conditions.

Palavras-chave : Tetrahydroisoquinoline; TIQ-diamine; Mitsunobu reaction.

        · texto em Inglês     · Inglês ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License