South African Journal of Chemistry
On-line version ISSN 1996-840X
Print version ISSN 0379-4350
ASUNDARIA, Shahrukh T.; PATEL, Shreyas A.; MEHTA, Kalpesh M. and PATEL, Keshav C.. Synthesis, characterization and antimicrobial studies of some novel 1,3,4-thiadiazolium-2-thiolate derivatives. S.Afr.j.chem. (Online) [online]. 2010, vol.63, pp.141-144. ISSN 1996-840X.
In this study, ten new 5-substituted-3-[4,6-di(morpholine-4-yl)-1,3,5-triazine-2-yl]-1,3,5-thiadiazolium-2-thiolate 6(a-j) were prepared via a five step procedure from the starting material 1,3,5-triazine (1). Structures of all synthesized compounds were confirmed by spectral data and elemental analyses. Newly synthesized compounds were tested for their antibacterial and antifungal activities against some important bacterial and fungal species. Some of the compounds were found to be moderately active against the tested organisms.
Keywords : Thiadiazol; s-triazine; mesoionic; NMR spectroscopy; IR spectroscopy.