SciELO - Scientific Electronic Library Online

 
vol.63Grade 12 achievement rating scales in the new National Senior Certificate as indication of preparedness for tertiary chemistryThe synthesis of substituted piperazine-cholesterol conjugates for use as components of nucleic acid transfection lipoplexes índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Em processo de indexaçãoSimilares em Google

Compartilhar


South African Journal of Chemistry

versão On-line ISSN 1996-840X

Resumo

JASOURI, S.; KHALAFY, J.; BADALI, M.  e  PILTAN, M.. Selective bromination of 4-chloro-1-indanone and synthesis of (4-chloro-2, 3-dihydro-1H-indene-2-yl)methanamine. S.Afr.j.chem. (Online) [online]. 2010, vol.63, pp. 83-87. ISSN 1996-840X.

The synthesis of 4-chloro-1-indanone in four steps from 2-chlorobenzaldehyde was investigated. Bromination of this compound under various conditions occurred in the cyclopentanone ring, producing mono- and dibromo derivatives. Cyanation of 2-bromo-4-chloro-1-indanone followed by reduction gave (4-chloro-2, 3-dihydro-1H-indene-2-yl)methanamine in quantitative yield.

Palavras-chave : Indanone; bromination; cyanation; reduction; GABAB receptors.

        · texto em Inglês     · Inglês ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License