South African Journal of Chemistry
On-line version ISSN 1996-840X
Print version ISSN 0379-4350
BUDAK, Yakup; FINDIK, Esra and CEYLAN, Mustafa. Cyclohexenones through addition of ethyl acetoacetate to 3-aryl-1-(thiophen-3-yl)prop-2-en-1-one derivatives. S.Afr.j.chem. (Online) [online]. 2010, vol.63, pp.01-10. ISSN 1996-840X.
Chalcone derivatives 3a-i: containing a thiophene ring were prepared by the condensation of 1-(thiophen-3-yl)ethanone with aromatic aldehydes in excellent yields. The Michael addition of ethyl acetoacetate 4 to chalcone derivatives 3a-i: resulted in the formation of nine novel ethyl 6-aryl-4-(3-thienyl)cyclohex-3-en-2-one-1-carboxylate derivatives 6a-i
Keywords : Michael addition; ethyl acetoacetate; cyclohexenones; cyclocondensation.