South African Journal of Chemistry
versão On-line ISSN 1996-840X
JANSE VAN RENSBURG, Caryl K.A. e ROBINSON, Ross S.. Synthesis of oxo- and thio-analogues of 2-oxo-2H-chromen-7-yl dimethylcarbamates. S.Afr.j.chem. (Online) [online]. 2009, vol.62, pp. 143-148. ISSN 1996-840X.
A range of novel 2-oxo-2H-chromen-7-yl dimethylcarbamates was synthesized containing either an oxygen or sulphur atom in the α-position to the carbonyl or thiocarbonyl group of the amide moiety. The synthesis and spectroscopic data of these compounds are reported. Microwave synthesis was essential for the successful synthesis of some of the sulphur-containing carbamates. The synthesized compounds will be used in a subsequent study on the influence of the α -substituent on the amide rotational barrier.
Palavras-chave : rotational barrier; thiocarbamates.