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South African Journal of Chemistry

versión On-line ISSN 1996-840X
versión impresa ISSN 0379-4350

Resumen

LI, Jian-Ping et al. Straightforward synthesis of a new series of α-(arylamino thiocarbonyloxy) hydrocarbylphosphonates. S.Afr.j.chem. (Online) [online]. 2008, vol.61, pp.05-08. ISSN 1996-840X.

A convenient, straightforward, two-step reaction of α-hydroxyhydrocarbylphosphonates with arylisothiocyanates in the presence of catalytic amounts of sodium methoxide in 1,2-dichloroethane as solvent produced various new α-(arylamino thiocarbonyloxy) hydrocarbylphosphonates in excellent yields. Their structures have been confirmed by their IR, 1H NMR and 31P NMR spectra and by elemental analysis. The preliminary antisepsis activity and protein activity of some of the compounds were identified.

Palabras clave : Phosphonates; arylisothiocyanates; A-hydroxyhydrocarbylphosphonates; synthesis; activity.

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