Abstract

ALLI, N A et al. Thrombotic disorders (part 2). SAMJ, S. Afr. med. j. [online]. 2020, vol.110, n.3, pp.181-187. ISSN 2078-5135.  http://dx.doi.org/10.7196/samj.2020.v110i3.14634.

Thromboembolic conditions are a leading cause of mortality, estimated to account for 1 in 4 deaths worldwide in 2010. Over time, the incidence and mortality rates of these conditions have declined in developed countries, but are increasing in developing countries. A delicate balance exists between procoagulant and anticoagulant factors within the vascular system. Numerous acquired or inherited conditions may tip the balance either way, i.e. towards a prothrombotic or prohaemorrhagic state. Acquired thrombotic disorders are the subject of discussion in this issue, the second of a 2-part series on thrombophilia.

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