SciELO - Scientific Electronic Library Online

 
vol.107 issue4Tuberous sclerosis complex in the Western Cape, South Africa: The clinical presentation featuresLead poisoning in shooting-range workers in Gauteng Province, South Africa: Two case studies author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Article

Indicators

Related links

  • On index processCited by Google
  • On index processSimilars in Google

Share


SAMJ: South African Medical Journal

On-line version ISSN 2078-5135
Print version ISSN 0256-9574

Abstract

NYO, M T L; MAGAZI, D  and  ALLY, M M T M. Systemic lupus erythematosus: A possible cause of non-alcoholic Wernicke's encephalopathy. SAMJ, S. Afr. med. j. [online]. 2017, vol.107, n.4, pp.299-301. ISSN 2078-5135.  http://dx.doi.org/10.7196/samj.2017.v107i4.12053.

We report a young woman with systemic lupus erythematosus (SLE) and an acute cerebellar ataxia. A history of poor appetite and vomiting preceded the inco-ordination. Ataxia in SLE has been well described, but is nevertheless uncommon. The clinical triad of mild confusion, ataxia and ophthalmoplegia also raised the possibility of Wernicke's encephalopathy (WE). The diagnosis of WE was further supported by the magnetic resonance imaging features. Owing to overlapping causal factors, this case illustrates the complexity of diagnosing and managing neuropsychiatric syndromes in a patient with SLE. The limited published literature on SLE-related cerebellar syndromes adds to the challenge. Gastrointestinal manifestations of SLE are described as being common in SLE, with nausea and vomiting occurring in >50% of cases in some series. Poor eating habits and vomiting are well-described causes of non-alcoholic WE. This is the first description of gastrointestinal SLE as a possible cause of WE.

        · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License