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SAMJ: South African Medical Journal

On-line version ISSN 2078-5135
Print version ISSN 0256-9574

Abstract

ABULFATHI, A A et al. Angio-oedema associated with colistin. SAMJ, S. Afr. med. j. [online]. 2016, vol.106, n.10, pp.990-991. ISSN 2078-5135.  http://dx.doi.org/10.7196/samj.2016.v106i10.10835.

A 50-year-old woman known to have type 1 diabetes mellitus presented with a rare case of angio-oedema associated with colistin use. The angio-oedema was temporally associated with the use and discontinuation of colistin with the reasonable exclusion of important differential diagnoses. Pseudoallergy may be a probable underlying mechanism. However, we cannot exclude the possibility of hereditary angio-oedema type 2 or 3, or that her concomitant medications (particularly enalapril) and her renal impairment contributed to the risk and severity of her angio-oedema.

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